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management differential infectiousdiseases rheumatology infections stills summary activation adultonset aosd arthritis bacteria bronchiectasis cap cardiology causes classification clinical community cutaneous
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Differential Diaqnoses ... Complications: MAS ... hepatitis • Pulmonary ... #treatment #rheumatology
Rhodococcus - Microbiology Overview Microbiology: • Facultative, intracellular, nonmotile, non-spore-forming • Aerobic acid-fast gram-positive coccobacilli • Produces
Transmission (Zoonotic disease ... inoculation due to trauma ... Diagnosis Treatment ... #diagnosis #treatment ... #pulmonary #Bacteria
Classification of Diabetes Insipidus Central or neurogenic diabetes insipidus: - Congenital - Structural malformations affecting the hypothalamus
, Trauma, Surgery ... AQP-2 gene - Acquired ... insipidus: - Acquired ... Treatment is aimed ... Types #Nephrology #Diagnosis
Leptospirosis Pathogen: Leptospira (interrogans, kirschneri, noguchii) Risk Factors: • Occupational exposure - Farmers, ranchers, trappers, veterinarians • Recreational
Presentation: • Mild disease ... failure • Severe pulmonary ... disease ARDS Diagnosis ... Leptospirosis #Leptospira #microbiology ... #diagnosis #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
the secondary or acquired ... arthritis (sJIA) • Adult-onset ... Still disease ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis
Tularemia - Diagnosis and Management Summary Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection •
More common in adults ... Culture & GS, PCR Treatment ... : • Severe Disease ... #management #treatment ... infectiousdiseases #microbiology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... Treatment - Mild ... : NSAIDS Treatment ... anti-lL6R, anti-ILI #Adult
Septic Arthritis - Diagnosis and Management Summary Clinical Exam: hot, swollen, pain with passive AND active ROM
osteomyelitis, trauma ... necrosis, Lyme disease ... Treatment: admission ... washout • Healthy Adults ... pediatrics but NOT adults
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Purtilo (XLP) Acquired ... • Autoimmune diseases ... : SLE+++, Adult-onset ... Still disease, ... #management #treatment
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
- Differential Diagnosis ... cell enzymes - Acquired ... • Pulmonary infarction ... Demand ischemia • Trauma ... #differential #diagnosis
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