11 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Differential Diaqnoses ... Complications: MAS ... hepatitis • Pulmonary ... #treatment #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Syndrome (MAS) ... the secondary or acquired ... manifestation of MAS ... Plasma exchange #MAS ... #Syndrome #Diagnosis
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Labs: • ↑ESR/CRP ... mL Gf consider MAS ... Treatment - Mild ... : NSAIDS Treatment
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
and M. fortuitum can ... ): • Acquired ... disease may complicate ... MAC pulmonary disease ... • Microbiologic
Community Acquired Pneumonia (CAP) - Diagnosis and Management

Pneumonia Signs/Symptoms:
 • Confusion/disorientation (LR + 1.9)
 • Cough
Community Acquired ... - Diagnosis and ... be initiated in adults ... #Diagnosis #Management ... #treatment #Pulmonary
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
- Differential Diagnosis ... the serum that has ... cell enzymes - Acquired ... • Pulmonary infarction ... Demand ischemia • Trauma
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
to find in an adult ... • Secondary (Acquired ... - Common in: Adults ... ▪ Autoimmune diseases ... (often termed MAS-HLH
Cutaneous larva migrans skin Rash
25 F recent Caribbean vacation, walked barefoot on sand and now with
with creepy rash. diagnosis ... with pruritus. can ... Adult hookworms ... No treatment is ... required unless
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
and Differential Diagnosis ... Hypercoagulable (APLAS) Microbiology ... Cerebral > Splenic, Pulmonary ... occlusion that may ... hematuria, + RF Treatment
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
, MGRS lesions can ... common in older adults ... Complement pathway activation ... microangiopathy Treatment ... #Significance #Diagnosis