19 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Differential Diaqnoses ... Complications: MAS ... hepatitis • Pulmonary ... #treatment #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Activation Syndrome (MAS ... the secondary or acquired ... arthritis (sJIA) • Adult-onset ... manifestation of MAS ... Plasma exchange #MAS
Rhodococcus - Microbiology Overview

Microbiology:
 • Facultative, intracellular, nonmotile, non-spore-forming
 • Aerobic acid-fast gram-positive coccobacilli
 • Produces
Transmission (Zoonotic disease ... inoculation due to trauma ... Diagnosis Treatment ... #diagnosis #treatment ... #pulmonary #Bacteria
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
failure • Severe pulmonary ... disease ARDS Diagnosis ... manifestations • MAT ... Leptospirosis #Leptospira #microbiology ... #diagnosis #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Purtilo (XLP) Acquired ... • Autoimmune diseases ... : SLE+++, Adult-onset ... Still disease, ... #summary #rheumatology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Polycythemia Vera (PV) - Diagnosis ... Management Summary Diagnostic ... with evidence of acquired ... von Willebrand disease ... #hematology
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
): • Acquired ... disease may complicate ... MAC pulmonary disease ... Diagnosis Of NTM ... • Microbiologic
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
- Differential Diagnosis ... the serum that has ... cell enzymes - Acquired ... • Pulmonary infarction ... Demand ischemia • Trauma
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... THROMBOSIS • Acquired ... Myeloproliferative disease ... • Surgery • Trauma ... #differential #diagnosis