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management differential disease hematology stills abscess activation adultonset amiodarone aosd bronchiectasis causes fungal hemeonc hemophagocytic hlh induced infections infectiousdiseases lymphohistiocytosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
arthritis (sJIA) • Adult-onset ... rash) • Heart, lung ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis ... #Rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Complications: MAS ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... antibiotics once stable ... hemorrhage • Treatment ... shows a small, stable ... #Abscess #pulmonary
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Other tests: • CT chest ... sparing of the lung ... typically seen on chest ... hemosiderin laden macrophages ... #management #treatment
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Amiodarone Induced Lung ... Direct cytotoxic lung ... starting amiodarone treatment ... pneumonitis Diagnosis ... Treatment:
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... is often on the chest ... mL Gf consider MAS ... Treatment - Mild ... #rheumatology #
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
in the adjacent lung ... of the affected lung ... parenchyma Diagnosis ... is abnormal in adults ... mycobacteria Treatment
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... Histoplasmosis Diagnosis ... aches, joint pain, chest ... change in the lungs ... nails, bronchi, lungs
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
granulomas within the lungs ... dysregulation: activated macrophages ... Pulmonary: dyspnea ... , cough, chest pain ... acute sarcoidosis Pulmonary
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
to find in an adult ... - Common in: Adults ... (often termed MAS-HLH ... : Macrophage Activation ... #Management #Hematology
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