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diagnosis management high causes differential syndrome tls hematology intercellularshift kdigo leukostasis oncology pseudohyperkalemia reverse uricacid
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• NSAIDs • ACE ... • Recent IV potassium ... Transfusion reaction - Tumor ... lysis syndrome ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• NSAIDs • ACE ... • Recent IV potassium ... Transfusion reaction - Tumor ... lysis syndrome ... #high #nephrology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: - Neuro: AMS ... organ damage • Treatment ... values: Elevated K, ... hydration - Hyperkalemia ... unless worrisome EKG
Emergent Hyperkalemia Treatment Algorithm ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Treatment Algorithm ... ECG changes, weakness ... injury, etc) ECG ... Remove potassium ... #Treatment #Algorithm
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... malignancies Treatments ... with Ca only if EKG ... Walid Malki, MD, MS ... #Lysis #Syndrome
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
, ACEi/ARBs, NSAIDs ... Acidosis, Cell Lysis ... heparinized tube) • ECG ... acidosis), CK+LDH (lysis ... #potassium #nephrology
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... (e.g. ... Tumor Lysis Syndrome ... Decreased Na+-K+ ... IntercellularShift #Nephrology
KDIGO Treatment algorithm for management of acute hyperkalemia in the emergency department • Place on cardiac
KDIGO Treatment ... monitor 12-lead ECG ... depletion • Consider K+ ... #treatment #potassium ... #high #nephrology
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... Algorithm • IV ... depletion • Consider K+ ... and ECG changes ... #treatment
Pseudohyperkalemia vs Reverse Hyperkalemia Pseudohyperkalemia and reverse pseudohyperkalemia are both conditions where potassium levels appear falsely elevated. Pseudohyperkalemia: This
especially extreme, e.g ... • ECG findings ... no changes in ECG ... despite high K+ ... #Potassium #Nephrology
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