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diagnosis management signs withdrawal differential neurology psychiatry timeline treatment addiction alcoholusedisorder anticonvulsants cerebritis cns deliriumtremens emergency encephalopathy erythematosus hematology leukostasis
Alcohol Use Disorder: Pathogenesis and Clinical Findings • Tolerance (reduced sensitivity to effects of EtOH) •
• Withdrawal symptoms ... , tachycardia, nausea ... tremor, insomnia, seizure ... #Pathophysiology ... Diagnosis #Signs #Symptoms
Alcohol Withdrawal Syndrome (AWS) - ICU OnePager Scoring Alcohol Withdrawal Syndrome (AWS): • PAWSS • CIWA-Ar •
Syndrome (AWS) ... Withdrawal Symptom ... Minor Withdrawal Symptoms ... • Withdrawal Seizures ... treatment #management #etoh
Alcohol Withdrawal: Clinical Findings and Complications The onset of alcohol withdrawal generally begins 6-24 hours after the
>2 days after EtOH ... dreams, anorexia, nausea ... , headache and psychomotor ... #Pathophysiology ... #EtOH
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
changes and may cause ... History of excessive alcohol ... overload) Other Symptoms ... Rhabdomyolysis • Seizures ... Differential #Diagnosis #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Dehydration • Symptoms ... : • Pathophysiology ... dysrhythmias, seizures
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
characterized by: • Headache ... mental status • Headache ... Etiology: • Pathophysiology ... Neurological symptoms ... edema visualized as
Time course of events during the alcohol withdrawal syndrome. The signs and symptoms that manifest earliest
withdrawal syndrome ... The signs and symptoms ... palpitations, nausea ... and seizures. ... The earliest symptoms
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
Anticonvulsants as ... Stevens-Johnson Syndrome ... -> Withdrawal seizure ... ataxia, asthenia, headache ... #SideEffects #Pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... , Headache, Movement ... disorders, Seizure ... Disease, PRES Pathophysiology ... autoantibodies that will cause
Emergent Causes of Headache and Associated Risk Factors Carbon monoxide poisoning - Breathing in enclosed or confined
Emergent Causes ... with the same symptoms ... vasoconstriction syndrome ... neurological findings or seizure ... - History of alcohol
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