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diagnosis differential algorithm causes management oncology workup aplastic disorders encephalopathy hepatic leukemia macrocytic microcytic neutropenia platelet platelets thrombocytopenia thrombocytosis treatment
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... workup, including BM ... • Nonmalignant hematologic ... hemolysis, deficiency anemia ... Diagnosis #Algorithm #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... in bone marrow (BM ... under 2%, then BM ... for degree of anemia ... Diagnosis #Workup #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
changes), high MCV anemia ... or if a primary hematologic ... When do you do a BM ... Causes #Workup #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Toxic injury to BM ... Immune Aplastic Anemia ... #oncology #hematology
Hepatic Encephalopathy Treatment • Lactulose: - Oral liquid, 30-45mL 2-4x/day, titrated to 2-4
titrated to 2-4 BMs ... swallow) - Via enema ... Treatment #management #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
cells - Blood & BM ... • Cytopenia -> BM ... - infiltrates (anemia ... #Leukemia #Hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
replacing the BM ... Megaloblastic anemia-rare ... replacing the BM-common ... diagnosis #causes #hematology
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