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diagnosis clinical differential algorithm aplastic body bonemarrow causes cd138 disease graft gvhd leukemia management microscopy myeloma neutropenia plasmacells platelets russellbodies
Acute Graft versus Host disease: vacuolar interface dermatitis w/ lymphoexocytosis, dyskeratotic keratinocytes, notable satellite cell necrosis.
Acute Graft versus Host ... more sparse after BMT ... Graft #versus #Host ... #disease #Pathology ... #Microscopy #Dermatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... workup, including BM ... • Nonmalignant hematologic ... hemolysis, deficiency anemia ... Diagnosis #Algorithm #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Toxic injury to BM ... Immune Aplastic Anemia ... #oncology #hematology
Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies). They're difficult to identify
Myeloma: In this BM ... core, most plasma ... BoneMarrow #Clinical #Pathology ... #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
cells - Blood & BM ... • Cytopenia -> BM ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
replacing the BM ... Megaloblastic anemia-rare ... drug reactions-most ... replacing the BM-common ... diagnosis #causes #hematology
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