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differential algorithm causes clinical leukemia workup aplastic body bonemarrow cd138 disease disorders graft gvhd hemepath largegranular lymphocytic macrocytic management microcytic
Acute Graft versus Host disease: vacuolar interface dermatitis w/ lymphoexocytosis, dyskeratotic keratinocytes, notable satellite cell necrosis.
Acute Graft versus Host ... more sparse after BMT ... Graft #versus #Host ... #disease #Pathology ... #Microscopy #Dermatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... workup, including BM ... hemolysis, deficiency anemia ... #Algorithm #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... in bone marrow (BM ... under 2%, then BM ... #Algorithm #Diagnosis ... #Workup #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Toxic injury to BM ... #oncology #hematology ... #diagnosis #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... changes), high MCV anemia ... When do you do a BM ... #Differential #Diagnosis ... Causes #Workup #hematology
Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies). They're difficult to identify
Myeloma: In this BM ... core, most plasma ... BoneMarrow #Clinical #Pathology ... #Hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... replacing the BM ... Megaloblastic anemia-rare ... replacing the BM-common ... #causes #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
cells - Blood & BM ... • Cytopenia -> BM ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia Clinical - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
autoimmune disease - Most ... Neutropenia (85%), anemia ... presentation (PB, BM ... Leukemia #hemepath #pathology ... #diagnosis
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