74 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: • Vascular occlusion ... - Hemolytic anemia ... SLE) - Viral infections ... Kasabach-Merritt syndrome ... Differential #Diagnosis #hematology
Causes of Pleural Effusion - Differential Diagnosis Algorithm
Transudate - Hydrostatic
 • Congestive heart failure
 • Constrictive
Causes of Pleural ... Urinothorax Exudate - Infectious ... Malignancy • Pulmonary ... • Asbestos • Uremia ... #causes
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... - HIV infection ... Chronic hemolytic anemia ... veno-occlusive ... #Differential #Causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... differential #diagnosis #hematology ... #anemia
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Causes of Ascites ... - Budd-Chiari syndrome ... - Veno-occlusive ... Portal vein occlusion ... SAAG < 1.1 g/dL) Infections
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... autoimmune hemolytic anemia ... DDX - Other causes ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Neoplastic / Hematologic ... • Anemia • ... Malignancy Infectious ... Disease Neurologic ... Chronic Fatigue Syndrome
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Weakness • Cardio-pulmonary ... diseaseAnemia ... • Chronic Infection ... Lambert-Eaton Myasthenic Syndrome
Right-Sided Heart Failure - Differential Diagnosis Algorithm
Cardiac Causes - Rule out Left-Sided Heart Failure (Most Common):
Algorithm Cardiac Causes ... Disease • ... Respiratory Distress Syndrome ... • Chronic Lung Infection ... Veno-Occlusive
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... risk-stratification • Risks: infection ... #treatment #hematology