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hematology causes treatment algorithm liver classification criticalcare disease gastroenterology neurology pathophysiology rheumatology aflp endocrinology foamed hepatitis obstetrics oncology overview pregnancy
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic - less common ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... #Diagnosis #Management
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Bile Ducts • Common ... • Others #LFTs ... #Hepatology #LiverEnzymes
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Common Etiologies ... disease (Budd-Chiari syndrome ... 14 percent) #Diagnosis ... #Differential # ... Hepatology #Cirrhosis
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 Hypocalcemia - Diagnosis and Management PTH Independent (↑ PTH) • LOW VIT D -
Hypocalcemia - Diagnosis ... and Management ... - Activation: Liver ... Iatrogenic (most common ... #differential #
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
presence of metabolic syndrome ... #LFTs #Abnormal ... #Algorithm #Hepatology ... #Differential # ... Diagnosis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... • Gilbert's syndrome ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... • Incidence: common ... initiation • Differential ... Differentiation #Syndrome ... #management #hematology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... Diagnosis Portal ... >10 mmHg - clinically ... #Diagnosis #causes ... #hepatology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
and less common ... MRI lesions and clinical ... consistent with MS ... noninflammatory #differential ... #diagnosis
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Highly variable clinical ... arthralgias) are common ... Muscle Abs (ASMA) (common ... Hepatitis (eg Viral) Management ... #Management #Hepatology
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