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diagnosis liver transaminitis algorithm hepatitis hepatocellular aflp aih autoimmune chemistry dili drug enzymes fatty gastroenterology idiosyncratic induced interpretation obgyn obstetrics
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... Liver Injury ... Liver Injury? ... Transaminitis #diagnosis #differential ... #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... Mixed DILI • Cholestatic ... #differential # ... gastroenterology #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury → liver ... Injury Differential ... #Injury #Differential ... Transaminitis #LFTs
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... injury < 26 weeks ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
infiltration) Differential ... , Intrahepatic Cholestasis ... Management: • ... Maternal Support - Critical ... #Pregnancy #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
injury, though ... cholestatic pattern ... Hepatitis (eg Viral) Management ... AIH #Diagnosis #Management ... #Hepatology
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