39 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Fatty Liver of ... Hemolysis, Elevated Liver ... exchange 3) Fatty liver ... coagulation defects and liver ... #AFLP #obstetrics
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... Hemolysis, Elevated Liver ... exchange 2) Fatty liver ... coagulation defects and liver ... #AFLP #Obstetrics
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Hepatocellular - Liver ... biliary obstruction, HELLP ... Syndrome, Celiac ... Artery: Shock Liver
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Syndrome (Hemolysis ... , Elevated Liver ... features: Liver ... BrighamChiefs #Liver
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Transaminitis - Differential ... • Congenital: HELLP ... Trauma: Shock liver ... #Diagnosis #causes ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... malaise) → Acute liver ... Preeclampsia, HELLP ... Transfer to a liver
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... : • Liver disease ... TTP, HUS, DIC, HELLP ... Hemolytic #Anemia #Differential ... classification #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Pregnancy - AFLP, HELLP ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Myelodysplastic Syndromes ... WBCs - Normal Liver ... Deficiency - Abnormal Liver ... Tests • Liver ... #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Algorithm Vascular Causes ... vein: Budd-chiari syndrome ... • Pregnancy: HELLP ... diagnosis #algorithm #hepatology