15 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Syndrome and Acute ... Three syndromes ... child * Severe cases ... #AFLP #obstetrics ... #hematology #diagnosis
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Three syndromes ... child * Severe cases ... #TTPHUS #HELLP ... #AFLP #Obstetrics ... #OBGyn #Hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
, no necrosis HELLP ... Syndrome (Hemolysis ... #hepatology #obstetrics ... hepatitis #comparison #differential ... diagnosis #icp #HELLP
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... biliary obstruction, HELLP ... Syndrome, Celiac ... Toxic: Medication, Pregnancy ... Acute #algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... infiltration) Differential ... Preeclampsia, HELLP ... #Pregnancy #hepatology ... #obstetrics #obgyn
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Transaminitis - Differential ... • Congenital: HELLP ... Trauma: Shock liver ... #Diagnosis #causes ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Wilson's • Pregnancy ... - AFLP, HELLP ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... antiphospholipid syndrome ... - Pregnancy: HELLP ... Diagnosis #Framework #hematology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... of pregnancy ... #Diagnosis #causes ... #hepatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Volume (MCV) - Differential ... Pregnancy) - Low ... Myelodysplastic Syndromes ... #Hematology