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differential hematology management causes infections rheumatology symptoms hemophagocytic hepatology hlh lactate liver lymphohistiocytosis physicalexam workup acidosis activation acute adrenalmass agglutinin
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Algorithm Normal ... Myelodysplastic Syndromes ... Tests • Rule ... Tests • Liver
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... liver blood tests ... symptoms/signs ... presence of metabolic syndrome
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... Orange or Hep C Clinical ... Lymphadenopathy • Fevers ... Physical Exam/Signs ... • Neutropenia, anemia
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Returning Traveler’ algorithm ... Test for the respective ... thin smear • Signs ... node biopsy • Clinical ... UnknownOrigin #workup #diagnosis
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... Defects, Drugs, Liver ... anemia, Thalassemias ... Laboratory Tests ... Blood Smear ↑ abnormal
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... schistosomiasis • Pyemia ... Brucellosis Faget's Sign ... Brucellosis • Liver ... #Differential #Diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... Symptoms: High fevers ... Test: Donath-Landsteiner ... test #cold #
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary Clinical features - Classic triad (flank pain, hematuria,
Renal Cell Carcinoma ... Management Summary Clinical ... Anemia (common) ... night sweats, fever ... Budd Chiari syndrome
Signs and Symptoms Associated With Different Headache Etiologies • Nonfocal mental status changes - Meningitis, encephalitis,
Signs and Symptoms ... Hypertension with normal ... coital headache • Fever ... #headache #signs ... #differential #diagnosis
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
- Differential Diagnosis ... RBCs, muscle, liver ... upon damage • Normal ... myocarditis, rheumatic fever ... • Tumor lysis syndrome
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