13 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Fatty Liver of ... Hemolysis, Elevated Liver ... tests, Low Platelets ... exchange 3) Fatty liver ... #hematology #diagnosis
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... Hemolysis, Elevated Liver ... tests, Low Platelets ... exchange 2) Fatty liver ... coagulation defects and liver
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... Wilsons, Pregnancy - AFLP ... , HELLP • Moderate
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Syndrome (Hemolysis ... , Elevated Liver ... features: Liver ... #icp #HELLP #AFLP
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... vein: Budd-chiari syndrome ... • Pregnancy: HELLP ... extrahepatic source - Tests ... • Gilbert's syndrome
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... Preeclampsia, HELLP ... Transfer to a liver ... #Fatty #Liver #
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... response to abnormal liver ... derangement of liver ... the pattern of liver ... presence of metabolic syndrome
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
TTP, HUS, DIC, HELLP ... Drug-associated, PCH, Evans Syndrome ... Defects, Drugs, Liver ... Laboratory Tests ... #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... synthesized in: liver ... respiratory failure • Neurologic ... Hyophosphatasia #hepatology ... #diagnosis
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... the setting of liver ... shunt (Type 2) Clinical ... • Underlying liver ... hypertension • Liver