28 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Acute Fatty Liver ... Hemolysis, Elevated Liver ... tests, Low Platelets ... exchange 3) Fatty liver ... #obstetrics #hematology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... specific for the liver ... SinaiBmoreIMRes #Liver ... Transaminitis #diagnosis ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... Wilsons, Pregnancy - AFLP ... #hepatology #LiverFunctionTests
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... Hemolysis, Elevated Liver ... exchange 2) Fatty liver ... coagulation defects and liver ... Obstetrics #OBGyn #Hematology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... derangement of liver ... the pattern of liver ... presence of metabolic syndrome ... Abnormal #Algorithm #Hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... necrosis HELLP Syndrome ... Hemolysis, Elevated Liver ... features: Liver ... Disease #Pregnancy #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... vein: Budd-chiari syndrome ... extrahepatic source - Tests ... • Gilbert's syndrome ... #algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... Transfer to a liver ... #Fatty #Liver # ... Pregnancy #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Identify Acute Liver ... • Gilbert's syndrome ... #chemistry #diagnosis ... #differential #Hepatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Myelodysplastic Syndromes ... WBCs - Normal Liver ... Deficiency - Abnormal Liver ... • Liver Disease ... Algorithm #Causes #Hematology