10 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
of Pregnancy (AFLP ... tests, Low Platelets ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology ... #diagnosis #table
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... tests, Low Platelets ... TTPHUS #HELLP #AFLP ... #Obstetrics #OBGyn ... #Hematology #Diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... vein: Budd-chiari syndrome ... specificity to elevated ALP ... GGT/5-NT: ↑ - ALP ... extrahepatic source - Tests
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Differential Diagnosis ... iMedEducation #AFLP ... Pregnancy #hepatology ... #obstetrics #obgyn
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
necrosis HELLP Syndrome ... of Pregnancy (AFLP ... #obstetrics #hepatitis ... #differential #diagnosis ... #icp #HELLP #AFLP
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
presence of metabolic syndrome ... Areas of diagnostic ... ALP, alkaline phosphatase ... Abnormal #Algorithm #Hepatology ... #Differential #Diagnosis
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... in 1923 Low ALP ... synthesized in: liver ... respiratory failure • Neurologic ... Hyophosphatasia #hepatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
for All Types of ... profile, including liver ... (to support a diagnosis ... ANA and RF (if clinical ... laboratory #workup #diagnosis
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
-15% If SLE is clinically ... suspected, tests ... overlap syndromes ... erythematosus #diagnosis ... table #ANA
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... function tests ... #Diagnosis #Management ... #Hematology #Rheumatology