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diagnosis hematology differential syndrome algorithm leukemia causes chronic cll erythematosus generalized lupus lymphocytic product pruritus reactions secondary signs sle symptoms
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... , McLeod blood group ... IgM associated lymphoma ... , Malignant lymphoma ... differential #diagnosis #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
== Blood Glucose ... Cholestatic liver disease ... renal failure/uremia ... Differential: • Lymphoma ... #generalized #dermatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... deficiency • Fanconi’s anemia ... • Leukemia • Lymphoma ... : • Systemic lupus ... Differential #Diagnosis #Hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... • Non-Hodgkin lymphoma ... • Angiocentric lymphoma ... vasculitis (inflamed blood ... rash #diagnosis #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hematologic: Acute blood ... hemolysis, deficiency anemia ... Metastatic cancer, Lymphoma ... Diagnosis #Algorithm #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... pain (20%) Renal disease ... Glomerulonephritis Myositis(5%) Blood ... (75%): Anemia ( ... symptoms #diagnosis #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... cells can indicate disease ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Marginal Zone Lymphoma ... Alpha & Mu) Skin ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... number of sites of disease ... classification #hematology ... #oncology #management
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Diagnosis Algorithm Blood ... Differential: • Lymphoma ... Pruritus #secondary #systemic ... #generalized #dermatology
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