79 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
canagliflozin 2) Osmotic ... Sites #Action #nephrology
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Acetazolamide 2) Osmotic ... Pathophysiology #Nephrology
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
inhibitor) 2) Osmotic ... #pharmacology #nephrology
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Diuretics • Osmotic ... Diagnosis #Causes #nephrology
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
• Triamterene OSMOTIC ... summary #table #nephrology
Horizontal Nystagmus on Ocular Examination

Dr Prasad Jain @DrPrasadJain

#Horizontal #Nystagmus #Ocular #PhysicalExam #clinical #video #neurology #ophthalmology
Horizontal Nystagmus on Ocular ... Horizontal #Nystagmus #Ocular ... clinical #video #neurology ... #ophthalmology
Pendular Nystagmus on Ocular Exam

Pendular nystagmus seen in this patient with multiple sclerosis

#Pendular #Nystagmus #Ocular #PhysicalExam
Pendular Nystagmus on Ocular ... Pendular #Nystagmus #Ocular ... clinical #video #ophthalmology ... multiple #sclerosis #neurology
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
CAR-T therapy • Osmotic ... diagnosis #algorithm #nephrology
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
administration • Osmotic ... Hypernatremia #Nephrology
Hyponatremia Correction
1. Indications for Hypertonic Saline: seizure, coma, focal findings
   - typically occurs with
Hyponatremia → Osmotic ... rate #management #nephrology