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diagnosis hematology management classification differential mds myelodysplastic acidosis addiction aplastic cows elevation encephalopathy hepatic hepatology hodgkins lactate lactic leukemia lymphoma
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Toxic injury to BM ... and petechiae Causes ... Treatment: ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Out Secondary Causes ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... diagnosis #hematology #oncology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Causes of Lactate ... perfusion - shock->treatments ... thorough physical assessment ... before beginning treatment ... 30mmHg) - Severe anemia
Clinical Opioid Withdrawal Score (COWS) Resting Pulse Rate: Record beats per minute after patient is sitting or
Observation during assessment ... last ½ hour • 2 - nausea ... or twice during assessment ... Hospital Opioid Use Treatment ... Withdrawal #Scale #Buprenorphine
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Treatment ... classification #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
cells - Blood & BM ... • Cytopenia -> BM ... -> AML: Blast crises ... - infiltrates (anemia ... Leukemia #Hematology #Oncology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Causes of Neutropenia ... hypertension and/or drug treatment ... replacing the BM ... Megaloblastic anemia-rare ... replacing the BM-common
Hepatic Encephalopathy Treatment • Lactulose: - Oral liquid, 30-45mL 2-4x/day, titrated to 2-4
Encephalopathy Treatment ... titrated to 2-4 BMs ... swallow) - Via enema ... For refractory cases ... Encephalopathy #Treatment
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