9 results
Drugs Commonly Implicated as Triggers of Drug Induced Thrombocytopenia
#Diagnosis #Hematology #Thrombocytopenia #Differential #DrugInduced #Medications
Drugs Commonly Implicated ... as Triggers of Drug ... #Diagnosis #Hematology ... #Thrombocytopenia ... #Differential #DrugInduced
Drug-Induced Thrombocytopenia
The diagnosis of drug-induced thrombocytopenia can be made only by demonstrating resolution of thrombocytopenia once
Drug-Induced Thrombocytopenia ... The diagnosis of drug-induced ... once a suspected drug ... #Diagnosis #Hematology ... #Differential #DrugInduced
Drug-Induced Liver Injury - Pathophysiology
Indirect
Idiosyncratic
Direct

BWH Medicine Chiefs @BrighamChiefs

#DILI #DrugInduced #Liver #Injury #Pathophysiology #hepatology
Drug-Induced Liver ... Injury - Pathophysiology ... BrighamChiefs #DILI #DrugInduced ... Liver #Injury #Pathophysiology ... #hepatology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Thrombotic Microangiopathies ... - Primary Thrombotic ... Thrombocytopenic ... Complement-mediated TMA - Drug-induced ... Microangiopathy #TMA #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Intravenous Drug ... Pregnancy • Drugs ... Heparin-induced thrombocytopenia ... Venous #Arterial #pathophysiology ... #hematology #differential
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Heparin Induced Thrombocytopenia ... ♀, ↑Age, ESRD Pathophysiology ... consumption → thrombocytopenia ... emcrit.org/ibcc/thrombocytopenia ... Management #Treatment #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... - bleeding or thrombosis ... antibodies/SRA - + Thrombosis ... presence of large thrombosis ... treatment #management #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
syndrome - Thrombotic ... microangiopathy: Thrombotic ... thrombocytopenic ... infection) - Drugs ... differential #diagnosis #hematology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Thrombotic Microangiopathy ... triad of MAHA + thrombocytopenia ... Shiga-toxin HUS, drug-associated ... @AnnKumfer #Thrombotic ... Microangiopathy #TMAs #hematology