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diagnosis hematology algorithm differential hemophagocytic hlh lymphohistiocytosis signs symptoms apml behcet cardiology chf clinical differentiation disease foamed gout heartfailure hemeonc
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • ... WBC >100k, + lab signs ... of end organ damage ... TLS #diagnosis #management ... #hematology
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
SBP > 40 - End-organ ... • Obstructive: Pulmonary ... Abdominal compartment syndrome ... Differential #Diagnosis #criticalcare ... #management
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... Diagnosis: HLH signs ... with multiple organ ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... unless severe APLS, organ ... APML #diagnosis #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
inflammation of multiple organs ... Arthritis, AS Treatment ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... and damage of organs ... Pulmonary: dyspnea ... anterior/posterior MSK ... #Signs #Symptoms
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of congestion ... with presence of pulmonary ... acute coronary syndrome ... differential #algorithm #management ... heartfailure #chf #criticalcare
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
Diagnosis and Management ... sex • Metabolic syndrome ... double contour sign ... +Radiographic signs ... #treatment #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
, INC risk PE, Pulmonary ... phenomenon (16%) MSK ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... cytopenias and organ ... Persistent fever, organ ... Presentation • Common Signs ... #Hematology #HemeOnc
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