12 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... microglobulin Treatment ... or acute leukemia ... Leukemia #diagnosis #workup ... #oncology #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
for workup, including ... Rebound effect from treatment ... Metastatic cancer, Lymphoma ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Workup: • Full ... check for other organ ... Treatment • Early ... #oncology #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... : • Common: fever ... Renal Failure Treatment ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Headaches, bone pain, fever ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Lymphadenopathy • HSM • Fevers ... #Oncology #Diagnosis
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Syndrome Acute ... Retroviral Syndrome ... tissues, seeds the lymphoid ... Headache (45%) • Fever ... ) Treatment:
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... characterized by fever ... (malignancy), lymphoma ... Treatment: - Systemic ... #dermatology #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... - ACS, AKI, acute ... lab signs of end organ ... damage • Treatment ... diagnosis #management #hematology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
specific laboratory tests ... hypergammaglobulinemia, ↑ acute ... • "Reactive lymphoid ... management #phenotypes #workup ... #treatment #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... presents as an acute ... with multiple organ ... following: • Fever ... #hematology