22 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... Lymphadenopathy • Fevers ... microglobulin Treatment ... #workup #oncology ... #hematology
Disseminated Gonococcal Infection - Diagnosis and Management Summary

Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
the preferred test ... typically part of the workup ... • Test all patients ... : • Fever, chills ... Purulent Arthritis Syndrome
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
origin • Etiology ... - Pel-Ebstein fever ... translocation • Types: Classification ... Differential Diagnosis ... #differential #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
- Nonremitting fever ... Liver function tests ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Symptoms: High fevers ... Test: Donath-Landsteiner ... test #cold # ... hemolytic #anemia #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... • Induce blast cell ... Subacute-Acute: • Common: fever ... Renal Failure Treatment
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Renal Cell Carcinoma ... (RCC) - Diagnosis ... night sweats, fever ... Budd Chiari syndrome ... disease Imaging and Treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... lab signs of end organ ... damage • Treatment ... #TLS #diagnosis ... #management #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... agents given to organ ... factor (GCSF) treatments ... Workup: • Complete ... #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... with multiple organ ... following: • Fever ... Low or absent NK cell ... #hematology