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Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
HIT laboratory tests ... and to adjust treatment ... #Diagnosis #Management ... #Hematology #HIT ... #Heparin #Induced
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... 1,500 cells/µL Workup ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... and Management ... • Shear stress-induced ... #Management #treatment ... #hematology #differential
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Heparin Induced ... approach for post-test ... : Confirmatory test ... #Management #Treatment ... #Hematology #HemeOnc
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
potential for multiple organ ... months without treatment ... Hepatitis (AAH) Drug-Induced ... Failure #Cirrhosis #Hepatology ... #diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... • Immunologic Workup ... life-threatening • Treatment ... Erythematosus #Diagnosis ... #rheumatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
with response to treatment ... specific laboratory tests ... #management #phenotypes ... #workup #treatment ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... • Immunologic Workup ... comparison #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Initial screening test ... severe disease Treatment ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... endothelial damage • Induce ... Renal Failure Treatment ... unless severe APLS, organ ... #management #hematology