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diagnosis cardiology management anemia workup orthopedics abnormal electrocardiogram jointpain liver treatment bleeding bruising chronic clinical coagulation disorders elevatedmcv fatigue macrocytosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g ... #Causes #Hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
and the aPTT are ... (e.g. heparin contamination ... inhibitory drugs (e.g ... specific inhibitor (e.g ... #hematology #coagulation
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Diagnosis Algorithm ... Sepsis • Drugs (e.g ... (l and II) Hepatic ... #Causes #Hepatology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
- Differential ... Diagnosis Algorithm ... • Thrombus (e.g ... Myeloproliferative disorders (eg ... #Causes #Hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... to one factor e.g ... e.g. heparin ... inhibitory drugs e.g ... #hematology #coagulation
Liver Mass - Differential Diagnosis Algorithm Benign Cystic • Cyst • Polycystic Liver Disease • Caroli's
Liver Mass - Differential ... Diagnosis Algorithm ... • Metastases (e.g ... #Liver #Mass #Hepatology ... #Causes
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Causes of Neutrophilia ... Neutrophils - Differential ... Diagnosis Algorithm ... Solid Tumour (e.g ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... : INR/PT, aPTT(liver ... function test, ANA (e.g ... or if a primary hematologic ... #Workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... #differential # ... diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... inflammatory disorders (e.g ... Myelodysplastic syndrome ... #hematology #secondary
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