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diagnosis hematology management causes comparison disease leukemia table classification cppd gout joint lymphocytic mds myelodysplastic pain acidosis algorithm apml arterial
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... and other C Cell ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Allogeneic stem cell ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... lymphadenopathy and ... #Chronic #Lymphocytic ... #Leukemia #oncology ... #hematology #hemeonc
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic ... Acute bacterial and
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Pain in Sickle Cell ... predispose to other orthopedic ... common sites: hip, shoulder ... XR, MRI to dx and ... • Differentiate
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... factor (GCSF) treatments ... blood count with differential ... #diagnosis #hematology ... #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... • Induce blast cell ... initiation • Differential ... #oncology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
Summary Overview: chronic ... of hands/feet, knees ... , shoulders Signs ... imaging Treatment ... diagnosis #management #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... Evans • ITP • Cl-NH ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
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