8 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Imaging: CXR- pulmonary ... Differential Diagnosis: Infection ... Anaphylaxis, Acute Renal ... #management #hematology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... Renal Syndromes ... confirm DAH, r/o infection ... #Renal #Syndromes ... #treatment
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... irrigation • Management ... Torsemide) • Acute pulmonary ... Acute myocardial infarction ... Tolvaptan) • Treatment
IDSA - Approach to Treating a Patient With Diabetic Foot Osteomyelitis
When to consider a trial of
a Patient With Diabetic ... of nonsurgical treatment ... Persistent sepsis syndrome ... eg, presence of renal ... #nonoperative #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... Lymphadenitis, pulmonary ... leukoencephalopathy (PML ... #Inflammatory #Syndrome ... Differential #Diagnosis #Management
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
if SSTI or port infection ... abdominal pain; full infectious ... (~20 %) and APL ... , hypotension, renal ... failure, pulmonary
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
starting amiodarone treatment ... respiratory distress syndrome ... failure - Infectious ... macrophages Treatment ... #diagnosis #management
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... current treatment ... cardiovascular or pulmonary ... may result in an infection ... approved by the Food