3 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Imaging: CXR- pulmonary ... Anaphylaxis, Acute Renal ... Differentiation #Syndrome ... #oncology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome ... irrigation • Management ... and nephrotic syndrome ... and nephrotic syndrome ... disease • Liddle syndrome
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
TLS (tumor-lysis syndrome ... decompression SVC syndrome ... Hyperviscosity syndrome ... Cytokine-release syndrome ... Differentiation syndrome