9 results
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency - Differential ... Diuretic use - Renal ... HF • Moderate pulmonary ... renal failure: ... Manifestations #Differential
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... Acute or chronic ... Compensation, Acute ... (short bowel syndrome ... Classically” noted with pulmonary
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Dehydrogenase (LDH) - Differential ... Legionnaires disease • Pulmonary ... hepatitis • Acute ... paralyses CNS Disorders
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... cardiac output - Acute ... pulmonary edema ... - Compartment syndrome ... peritonitis - Acute
Bradycardia - Differential Diagnosis Framework

BRADI Mnemonic
 • BRASH/Hyperkalemia
 • Reduced oxygen/Glucose/Temp
 • ACS
 • Drugs
 •
Bradycardia - Differential ... Bradycardia • Renal ... Hyperkalemia Pulmonary ... • Congenital disorders ... Chagas disease • Acute
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Non-neuromuscular disorder ... (Cardiac, pulmonary ... Impairment: • Acute ... CPK aldolase, lactate
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Lung Diseases • Acute ... arthralgias, CV, renal ... Hypereosinophilic Syndrome ... parasites; Travel hx, food ... #differential #
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... Torsemide) • Acute ... pulmonary edema ... hyperaldosteronism • Acute ... specific bleeding disorders
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Imaging: CXR- pulmonary ... initiation • Differential ... Renal Failure ... APML #diagnosis #management