127 results
diagnosis pathophysiology pharmacology management differential endocrinology algorithm clinical symptoms treatment causes hematology signs table cardiology immunology neurology radiology rheumatology allergy
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... GH excess prior ... GH excess after ... hemianopsia IGF-1 Overproduction ... #Excess #Overproduction
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... synthesis of IGF1R -> Activation ... /Symptoms: • GH ... abn lipid • GH ... GrowthHormone #GH
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
enlargement - If GH ... • GH stimulates ... adenomas are mixed GH ... level (↑Sens) - GH ... (Lanreotide) ± GH
Anaphylaxis: Pathogenesis Anaphylaxis is a Type 1 hypersensitivity reaction While the primary mechanism of anaphylaxis is mast cell
anaphylaxis is mast cell activation ... Inappropriate mast cell activation ... cells • ANS activation
Acromegaly Caused by over-secretion of growth hormone (GH) from the pituitary gland. The condition is rare
growth hormone (GH
The parasympathetic and sympathetic systems - Activation and inhibition pathways by organ system #Sympathetic #Parasympathetic #Systems #Pathways
sympathetic systems - Activation
Fibrinolysis. Fibrinolysis occurs when plasminogen is activated to plasmin under the influence of factors such as
tissue plasminogen activator ... thrornbolytic drugs by activating
Transplant Infections Timeline Pre-transplant: • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut) • Viruses: HSV (reactivation) Engraftment:
Viruses: HSV (reactivation ... Viruses: HSV (reactivation ... Viruses: CMV (reactivation ... ), VZV (reactivation ... ), CMV (reactivation
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... hemophagocytosis and cytokine overproduction ... MAS #Macrophage #Activation
Tranexamic Acid - Indications and Pharmacology Pharmacokinetics: • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Inhibits plasminogen activation ... reduces complement activation
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