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Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
GH excess prior ... • Other rare causes ... hemianopsia IGF-1 Overproduction ... #Excess #Overproduction ... signs #symptoms #endocrinology
Acromegaly Caused by over-secretion of growth hormone (GH) from the pituitary gland. The condition is rare
Acromegaly Caused ... growth hormone (GH ... Symptoms #Diagnosis #Endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... abn lipid • GH ... GrowthHormone #GH ... #FeedbackLoop #endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
• GH stimulates ... level (↑Sens) - GH ... (Lanreotide) ± GH ... or refractory cases ... Diagnosis #Management #Endocrinology
Sellar / Pituitary Mass - Differential Diagnosis Algorithm Adenoma - Primary Anterior Pituitary - Secreting
Prolactin • GH ... Diagnosis #Algorithm #endocrinology ... #causes
Causes of Hypercalcemia #Differential #Hypercalcemia #Diagnosis #Causes #Endocrinology
Causes of Hypercalcemia ... Hypercalcemia #Diagnosis #Causes ... #Endocrinology
Tall Stature - Differential Diagnosis Algorithm Normal Growth (BA=CA) • Familial Tall Stature • XYY Syndrome Obese BMI
Puberty Onset • GH ... Diagnosis #Algorithm #endocrinology ... #causes
Weight Gain / Obesity - Differential Diagnosis Algorithm Decreased Expenditure: • Sedentary Lifestyle • Smoking Cessation
Hypogonadism • GH ... Diagnosis #Algorithm #endocrinology ... #causes
Causes of Hypophosphatemia - Dr. Kenar Jhaveri @kdjhaveri #hypophosphatemia #Causes #Differential #Diagnosis #endocrinology #algorithm
Causes of Hypophosphatemia ... hypophosphatemia #Causes ... Differential #Diagnosis #endocrinology
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Cushing's Disease • GH ... Diagnosis #Algorithm #endocrinology ... #causes #pediatrics
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