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Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
GH excess prior ... GH excess after ... hemianopsia IGF-1 Overproduction ... Carpal Tunnel Syndrome ... #Excess #Overproduction
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
• GH stimulates ... adenomas are mixed GH ... Beckwith Wiedemann syndrome ... level (↑Sens) - GH ... (Lanreotide) ± GH
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... abn lipid • GH ... GrowthHormone #GH
Tall Stature - Differential Diagnosis Algorithm Normal Growth (BA=CA) • Familial Tall Stature • XYY Syndrome Obese BMI
Stature • XYY Syndrome ... Puberty Onset • GH ... Klinefelter's Syndrome ... • Soto's Syndrome ... • XYY Syndrome
Spinal Cord Injury Syndromes Complete, Incomplete, Paraplegia, Tetraplegia Incomplete Spinal Cord Syndromes: - Brown Sequard Syndrome - Anterior
Spinal Cord Injury Syndromes ... Brown Sequard Syndrome ... Anterior Cord Syndrome ... Posterior Cord Syndrome ... - Central Cord Syndrome
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
21 • Noonan Syndrome ... • Prader-Willi Syndrome ... Russell-Silver Syndrome ... • Turner Syndrome ... Cushing's Disease • GH
Central Cord Syndromes - Anterior Cord Syndrome - Central Cord Syndrome - Brown Sequard Syndrome #CentralCord #Syndromes
Central Cord Syndromes ... Anterior Cord Syndrome ... - Central Cord Syndrome ... Brown Sequard Syndrome ... #CentralCord #Syndromes
Inherited Colorectal Cancer (CRS) Syndromes Adenomatous Polyposis Syndromes: • Familial Adenomatous Polyposis (FAP), Attenuated FAP (AFAP), MUTYH
Colorectal Cancer (CRS) Syndromes ... Adenomatous Polyposis Syndromes ... Urinary → Lynch Syndrome ... Peutz-Jeghers Syndrome ... (JPS), Cowden Syndrome
Acromegaly Caused by over-secretion of growth hormone (GH) from the pituitary gland. The condition is rare
growth hormone (GH
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome: - Acute poststreptococcal glomerulonephritis - Rapidly progressive
and Nephrotic Syndromes ... Nephritic syndrome ... glomerulonephropathy) - Alport syndrome ... Nephrotic syndrome ... Nephritic #Nephrotic #Syndromes
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