17 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
suspect underlying hematologic ... disorders • Diagnosis ... #HES #Hematology ... #eosinophils #diagnosis ... #management #algorithm
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #hematology #rheumatology ... #nonpalpable #dermatology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
(HES) - Diagnosis ... and Management ... eosinophilia Secondary Causes ... Malignancy - Immunologic ... #hematology #differential
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
Disorders of Pigmentations ... sclerosis (white "ash ... McCune Albright syndrome ... #skin #dermatology ... #Algorithm #causes
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... vasculitis #Dermatologic ... Polyangiitis #GPA #dermatology ... #rash #diagnosis ... #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... lymphoproliferative disorders ... Drugs (Beta lactam antibiotics ... #hematology #anemia
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... with acne: antibiotics ... #Rheumatology # ... diagnosis #management ... #Dermatology
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
- Differential Diagnosis ... Eosinophilic GI Disorders ... cell activation syndrome ... Mastocytosis • Other hematologic ... #hematology #allergy
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... - Rash: multiple ... Causes: - Idiopathic ... , breast CA - Hematologic ... #diagnosis #dermatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... DDX - Other causes ... hypogammaglobulinemia #immunology ... #hematology #diagnosis ... #management