Overview treatment infectiousdiseases diagnosis algorithm disease workup syndrome infections differential disorders pediatrics hematology rheumatology antibodies antinuclear

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Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?

Diagnosis Algorithm ... → Refer to hematology ... for workup, including ... #Diagnosis #Algorithm ... #hematology

Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
• Artifact (redo CBC)
Autonomous:
• Essential thrombocytosis
• Polycythemia

Diagnosis Algorithm ... Myelofibrosis Infectious ... • Celiac disease ... #Diagnosis #Algorithm ... #Causes #Hematology

Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
1. Autoimmune Mediated Pancytopenia
2. Splenic Sequestration
Peripheral Destruction

and Differential ... Diagnosis Algorithm ... Metastatic Disease ... Diagnosis #Algorithm ... #Hematology

Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
• Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or

Eosinophil Disorders ... Testing Algorithm ... glucocorticoid treatment ... #Algorithm #Differential ... #diagnosis #hematology

Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like

Antinuclear Antibodies ... Lymphoproliferative Disorders ... , Infection, Autoimmune ... #patterns #rheumatology ... #diagnosis #differential

Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
•

Diagnosis Algorithm ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Diagnosis #Algorithm ... #Causes #Hematology

Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
- Prior platelet count, family

- Differential ... Diagnosis and Workup ... procedures - Infection ... anti-phospholipid antibodies ... #Workup #hematology

Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
1. Cold Agglutinins (CAD)
2. Donath-Landsteiner

Cold Sensitive Antibodies ... Cold Agglutinin Syndrome ... , autoimmune disorder ... younger pts) Differential ... hemolytic #anemia #hematology

Hemolytic Anemia - Differential Diagnosis Algorithm
• Sickle cells - Consider sickle cell disease (diverse genotypes):

Diagnosis Algorithm ... inclusions - If infection ... Consider RBC membrane disorder ... #Diagnosis #Algorithm ... #workup #hematology

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