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differential rheumatology dermatology anemia causes hemolytic leukemia lymphadenopathy management workup agep agglutinin allergy antinxp2 antinxp2dm arthritis chronic clinical cold dermatomyositis
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
- Differential Diagnosis ... Algorithm Cervical ... Lymphadenopathy #LAD ... #Algorithm #Causes ... #Hematology #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... pain, bleeding, infections ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Algorithm Reactive ... Lymphadenopathy #LAD ... #Algorithm #Causes ... #Hematology #Oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinins (CAD ... Agglutinin Disease (CAD ... , autoimmune disorder ... agglutination After CAD ... hemolytic #anemia #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Hepatomegaly • Skin ... lymphoproliferative disorders ... #workup #oncology ... #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... organ-specific signs ... symptoms (eg, skin ... #diagnosis #hematology
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Lymphoproliferative Disorders ... symptoms, unexplained hematologic ... rising EBV viral load ... , signs/symptoms ... #oncology #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... Consider sickle cell ... Consider RBC membrane disorder ... #hematology #testing
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... Episcleritis Signs ... general feeling of ill ... , breast CA - Hematologic ... #dermatology #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... Seizures • Strokes Skin ... • CAD APLA/LAC ... Erythematosus #Diagnosis
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