15 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... for workup, including ... Kawasaki, Nephrotic syndrome ... Matthew Ho, MD PhD ... #Differential #Diagnosis
Supracondylar Elbow Fracture
• Most common elbow fracture in children, peak age 5-7 
• When looking at
anterior sail sign ... posterior fat pad ... ), compartment syndrome ... • ED Management ... #XRay #Diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... can mimic common infections ... #management #treatment ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... permeability Diagnosis ... Lupus Cerebritis Induction ... #management #treatment
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
(SPS) - Diagnosis ... and Management ... Pathophysiology ... antibody that works ... #Management #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... : Infection (sepsis ... Differentiation #Syndrome ... #management #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... Differential Diagnosis ... fungal, viral infections ... #workup #hepatology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
shoe size, ↑ heel-pad ... malignancy Pathophysiology ... Beckwith Wiedemann syndrome ... and Workup: • ... #Treatment #Pathophysiology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... Physical Exam/Signs ... • Richter’s Syndrome ... #workup #oncology ... #hematology