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diagnosis differential headache management signs arteritis cardiomyopathy cirrhosis disorders emergency eosinophil eosinophilia erythematosus gca giantcell hemeonc hemophagocytic hepatology hlh lymphohistiocytosis
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... quadrant discomfort Signs ... autoimmune disease (e.g ... specific ANAs (e.g ... #hepatology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... aciduria, Drugs (e.g ... Matthew Ho, MD PhD ... #MCV #Algorithm ... Differential #Diagnosis #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... workup for specific symptoms ... organ-specific signs ... or symptoms (eg ... Differential #diagnosis #hematology
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
) • Systemic symptoms ... and signs (e.g. ... lesion • CNS infection ... (e.g., meningitis ... Matthew Ho, MD PhD
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... lymphopenia, low PLT • Anemia ... : • Symptoms limited
Emergent Causes of Headache and Associated Risk Factors Carbon monoxide poisoning - Breathing in enclosed or confined
carbon monoxide (eg ... living conditions (eg ... vascular diseases (eg ... , systemic lupus ... headache #redflags #signs
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... systemic complaints- anemia ... GCA #Temporal #Signs
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
(e.g., EBV) ... and Symptoms: ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g
Peripartum Cardiomyopathy (PPCM) What is PPCM? • A form of acute systolic heart failure that develops late in
of pregnancy (e.g ... maternal age • Anemia ... Genetic variants (e.g ... deficiencies (e.g ... Consider biomarkers (e.g
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