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diagnosis differential rheumatology arthritis management pain dermatology msk neurology syndrome workup approach autoimmune biliary cardiomyopathy cirrhosis conditions cryofibrinogenemia disease electrocardiogram
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... experienced briefly (e.g ... alterations (e.g ... subchondral bone (e.g ... derangements (e.g
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Bacterial or viral infection ... disease, Vasculitis (e.g ... ., PAN) • Seizures ... differential #diagnosis #rheumatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... organ-specific signs ... or symptoms (eg ... #diagnosis #hematology
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
quadrant discomfort Signs ... autoimmune disease (e.g ... Raynaud's phenomenon, arthritis ... specific ANAs (e.g ... #hepatology
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
) • Systemic symptoms ... and signs (e.g. ... (e.g., meningitis ... ) • Temporal arteritis ... Matthew Ho, MD PhD
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Approach to Joint ... Mechanical/degenerative disorders ... noninflammatory Signs ... constitutional symptoms ... Diagnosis #MSK #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
chronic inflammatory disorder ... Autoinflammatory disorder ... nonerosive inflammatory arthritis ... antiinflammatory properties e.g ... TNF blockers had
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Malignancy (e.g ... (e.g. thyroid disease ... : • Joint pain ... arthropathy • 90% joints ... Induced Lupus: • Symptoms
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... Episcleritis Signs ... and Symptoms: ... and pain of the joints ... , breast CA - Hematologic
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... GCA #Temporal #Signs ... #Symptoms #Diagnosis
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