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diagnosis syndrome treatment algorithm arteritis bells cardiomyopathy chagas differential differentiation disease gca giantcell headache hemeonc hemophagocytic hlh leukostasis lymphohistiocytosis lysis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Prednisone 5mg/kg ... common • Imaging: CXR ... Diagnosis: >3 symptoms ... #diagnosis #management ... #hematology #oncology
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
) • Systemic symptoms ... and signs (e.g. ... (e.g., meningitis ... Matthew Ho, MD PhD ... Diagnosis #Algorithm #neurology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... WBC >100k, + lab signs ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
ophthalmoplegia), systemic signs ... Imaging (if atypical symptoms ... ): MRI+gad (stroke ... inflammatory cause) • EMG ... #Treatment #Neurology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... #Management
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary Chagas disease (American trypanosomiasis) is an infectious
Diagnosis and Management ... Romana's sign ... /symptoms, positive ... serology, smear ... 20-90%, normal ECG
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
(e.g., EBV) ... and Symptoms: ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g
Peripartum Cardiomyopathy (PPCM) What is PPCM? • A form of acute systolic heart failure that develops late in
of pregnancy (e.g ... Genetic variants (e.g ... deficiencies (e.g ... Consider biomarkers (e.g ... congestion on a CXR
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