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diagnosis rheumatology dermatology algorithm erythematosus neurology oncology sle systemic acr2021 activation antinxp2 antinxp2dm apml arteritis bacterial capillary cerebritis chf clarksons
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Lumbar Puncture, EEG ... Cerebritis Induction ... cerebritis #diagnosis #management ... #treatment
Polyarteritis Nodosa (PAN) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Severe Disease → Remission
) - Vasculitis Management ... immunosuppressive agent (e.g ... Nodosa #Vasculitis #Management ... #Treatment #ACR2021 ... Guidelines #algorithm #rheumatology
Management of Polycystic Ovary Syndrome (PCOS) Hyperandrogenism, Family Planning, Endometrial cancer prevention, Cardiovascular risk factor management → Weight
Ovary Syndrome ... No FDA approved treatments ... Pregnancy - Ovulation induction ... Letrozole (BMI >30 kg ... #Management #endocrinology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
fibromyalgia) • Infections ... • Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... vein thrombosis Hematologic
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
WBC >100k, + lab signs ... organ damage • Treatment ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Serologic and EMG ... test - Cogan sign ... - Peek sign ... precipitated by: Drugs, infection ... Gravis #diagnosis #management
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... , breast CA - Hematologic ... - Lupus - Leukemia ... Treatment: - Systemic ... #diagnosis #dermatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... Diagnosis: HLH signs ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Prednisone 5mg/kg ... APML #diagnosis #management ... #hematology #oncology
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