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diagnosis algorithm differential management hematology checklist nephrology rheumatology evaluation pulmonary clinical treatment causes anesthesia anesthesiology endocrinology peds intraoperative criticalcare cardiology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
• Immunologic Workup ... 50-60% - pANCA
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... - Rare - pANCA ... • Immunologic Workup ... 50-60% - pANCA
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
ANCA-Associated ... - C-ANCA pattern ... antibody) - P-ANCA ... @AnnKumfer #ANCA ... #PANCA #MPO #PR3
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
• Immunologic Workup ... - Rare - pANCA
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... 80-90%) > MPO - ANCA ... MPO: 75-80% - ANCA ... disease - MPO>PR3 - ANCA ... Antinuclear #Antibody #ANCA
Causes of Approach to Altered Level of Consciousness - Workup Clinical Exam - Focal • Trauma •
Consciousness - Workup ... Refer to Blood Work ... Altered #ALOC #Workup ... #diagnosis #workup
Glomerulonephritis - Differential Diagnosis Framework ANCA: • C-ANCA: GPA (Wegener's) • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
Diagnosis Framework ANCA ... : • C-ANCA: GPA ... Wegener's) • P-ANCA
Approach to managing Glomerulonephritis (GN) in children. ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
ANCA, antineutrophil ... antibodies; c-ANCA ... hypertension; p-ANCA
ANCA Associated Vasculitis (AAV) - Auto-antibodies and Differential Diagnosis MPA → usually p-ANCA GPA → usually c-ANCA EGPA →
ANCA Associated ... MPA → usually p-ANCA ... EGPA → ANCA in ... 40-50% P-ANCA ... (MPO) C-ANCA (
Thrombocytopenia - Workup Algorithm A common consult I receive. Dr. Joseph Shatzel @Clotmaster #Thrombocytopenia #Workup #Algorithm #Diagnosis #Differential #Hematology
Thrombocytopenia - Workup ... Thrombocytopenia #Workup
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