8 results
Approach to Neonatal Jaundice

Causes of pathologic hyperbilirubinemia can be classified as due to (1) increased bilirubin
Approach to Neonatal Jaundice ... Causes of pathologic ... Pediatrics #Neonatal #Jaundice ... #Algorithm #Differential ... #Workup #bilirubinemia
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice ... Gilbert syndrome, Crigler-Najjar ... postoperative jaundice ... miscellaneous causes ... #differential #causes
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic Algorithm ... and Causes Increased ... Increased Serum bilirubin ... #Differential #Causes ... #Workup #Hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
breastfeeding jaundice ... and breastmilk jaundice ... manifest only as jaundice ... malaise, are common Crigler-Najjar ... and stress may cause
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... Diagnosis Algorithm ... Gilbert's Syndrome • Crigler-Najjar ... Cholangitis #Jaundice ... #Causes #Hepatology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... Algorithm and Differential ... osmolarity If cause ... , haptoglobin, bilirubin ... #Injury #AKI #Workup
Ascites - Diagnostic Approach and Differential Diagnosis
The most common causes: cirrhosis, malignancy and heart failure. Approx
The most common causes ... more than one cause ... carcinomatosis, HF ... brown: elevated bilirubin ... Jcortesizaguirr #Ascites #workup
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... hyperpigmentation • Jaundice ... slightly elevated • Bilirubin ... cholangitis #diagnosis #workup