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diagnosis management differential algorithm syndrome aplastic causes chronic disorders lymphocytic mds rheumatology treatment apml arthritis atlas blood cancer cell centralretinalartery
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... ALL (Acute Lymphoblastic ... - infiltrates (anemia ... ) CLL Symptoms: ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... • Neutropenia, anemia ... #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... transformation to acute ... leukemia Management ... Management #treatment #hematology ... #oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Diagnosis Algorithm Acute ... Disorders - Myelodysplastic ... Pelger-Huet, Macrocytic anemia ... • Lymphoid (CLL ... Blood #Disorders #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... progress to MDS or acute ... leukemia • Associated ... management #treatment #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... Workup: • Complete ... Syndromes #diagnosis #hematology ... #oncology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... Liver diseases, Myelodysplastic ... Malignant tumors, Acute ... #differential #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis): • Acute ... malignancies • Anemia ... vera (PV) • Myelodysplastic ... Chronic myeloid leukemia ... Diagnosis #Causes #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... Vmphocytosis on routine CBC ... of anemia or thrombocytopenia ... marrow failure with anemia ... #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
• Hypocellular myelodysplastic ... virus (EBV) • Leukemia ... • ↓ WBC • ↓ ... • Improve the symptoms ... #oncology #hematology
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