10 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... ’s lymphoma or acute ... #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
count ↑ PLT • ↑ PBS ... develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Hematology #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... transformation to acute ... leukemia Management ... treatment #hematology #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... virus (EBV) • Leukemia ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... #oncology #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... Episcleritis Signs ... - Lupus - Leukemia ... - CBC may also ... #dermatology #oncology
Checklist for Evaluation of New-Onset Delirium in the ICU

Initial assessment 
 - 
Vital signs, neuro exam
assessment - Vital signs ... /Mg/Phos - CBC ... tox/infectious workup ... Trauma - Acute ... #MICU #CriticalCare
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... Workup: • Complete ... diagnosis #hematology #oncology
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Shock, Severe Anemia ... Ischemia, Compartment Syndrome ... Beta-Agonists, ↑ work ... ), Malignancy (Leukemia ... Differential #Diagnosis #criticalcare
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Pleural effusions • Acute ... lymphopenia, low PLT • Anemia ... titers > 1:80 • CBC ... Hodgkin lymphoma and leukemia
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... • Plasma cell leukemia ... changes (POEMS syndrome ... Thalassemia, Sickle cell anemia ... inflammation (acute