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diagnosis hematology management myelodysplastic aecopd chronic cll copd differential exacerbation leukemia lymphocytic myelodysplasia platelets pulmonary syndrome syndromes thrombocytosis
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... Treatment: • Consider ... Can progress to MDS ... or acute leukemia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... • ↓ WBC • ↓ ... anemia Treatment ... #Anemia #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... cytopenias (usually anemia ... transformation to acute ... only curative treatment ... #hematology #oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... hematology for workup ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Matthew Ho, MD
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... Pure red cell aplasia ... ’s lymphoma or acute ... #oncology #hematology
Algorithm for Management of Acute Exacerbation of COPD (AECOPD) Obtain workup for alternate diagnoses and relevant comorbidities:
of Acute Exacerbation ... AECOPD) Obtain workup ... comorbidities: • CBC ... Matthew Ho, MD ... #Exacerbation #treatment
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Aplastic Anemia ... factor (GCSF) treatments ... Workup: • Complete ... diagnosis #hematology #oncology
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