118 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Diagnosis Algorithm Signs ... of anemia and hemolysis ... • Extrinsic RBC ... • Intrinsic RBC
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
is described as ... RBC are produced ... Approximately 1% of RBC ... destruction of RBC ... Mentzer index = (MCV/RBC
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
) - Summary PBC ... Signs and Symptoms ... Nucleotidase • ALT ... on but elevated as ... obstruction • ALP
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
quadrant discomfort Signs ... pregnancy Diagnose PBC ... Elevated ALP 2. ... consistent with PBC ... #PBC #Primary
Beevor's Sign on Physical Exam

Beevor's sign is abnormal upward (cephalad) movement of the umbilicus with truncal
Beevor's Sign on ... Exam Beevor's sign ... The sign been also ... been observed in ALS ... video #umbilicus #neurology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
of macrocytic anemia ... (RBC = red blood ... serum level for all ... elevated, but anemia ... recovery also causes
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... Even with normal WBC ... science/article/abs ... 21% had normal WBC ... #CBC #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... Triggers: Diuretics, PRBC ... : - Neuro: AMS ... • Lab values: WBC ... >100k, + lab signs
Mycophenolate Mofetil versus Cyclophosphamide for Induction Treatment of Lupus Nephritis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678035/

Mycophenolate versus Azathioprine as Maintenance Therapy
www.ncbi.nlm.nih.gov/pmc ... versus Azathioprine as ... NEJMoa1014460 #ALMS ... VisualAbstract #Nephrology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... to repair DNA, as ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓