16 results
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
CD10 - T-cell ... - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... - B-cell ... bcr-able (+) ↑ WBC
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Burr Cell RBC (Echinocyte ... Bite Cell RBC: G6PD ... disease Target Cell ... SC disease Red Cell
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Autoimmune hepatitis, PBC ... breast CA, small cell ... , Sickle cell, GVHD ... > 2 • NASH, Chronic ... diagnosis #algorithm #hepatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Lymphocytosis on CBC ... • Neutropenia, anemia ... #Chronic #Lymphocytic ... Leukemia #diagnosis #workup
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Mean corpuscular (cell ... Red cell distribution ... Normal range 11.5% ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Defects, Drugs, Liver ... Defects: Sickle cell ... anemia, Thalassemias ... Blood Smear ↑ abnormal ... Differential #Diagnosis #hematology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... > 2 • NASH, Chronic ... intestines, White blood cells ... #differential #Hepatology ... transaminitis #LFTs
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... low red blood cell ... Marrow Failure • Chronic ... Workup: • Complete ... Syndromes #diagnosis #hematology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... box indicates all ... biliary obstruction ... #LFTs #Abnormal ... #Algorithm #Hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... changes), high MCV anemia ... gastric bypass), LFT ... not required in all ... #hematology