14 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Prednisone 5mg/kg ... common • Imaging: CXR ... - pulmonary opacities ... #hematology #oncology
Algorithm for Management of Acute Exacerbation of COPD (AECOPD)

Obtain workup for alternate diagnoses and relevant comorbidities:
AECOPD) Obtain workup ... ventilated • CXR ... doppler, CTA • ECG ... #Exacerbation #treatment ... #pulmonary
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Blood cultures • CXR ... early disease) • CXR ... Clindamycin in case of PCN ... • Vasculitis (e.g ... Lung #Abscess #pulmonary
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... microglobulin Treatment ... Transform to DLBCL, PML ... #workup #oncology ... #hematology
Intraoperative  Bradycardia - Guidelines for Crises in Anaesthesia
Bradycardia in theatre should not be treated as
remember to tailor treatment ... reservoir bag and APL ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup #Cardiology
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
indicated, start CPR ... • Diagnostic ... thoracotomy is a better treatment ... Intraoperative #Checklist ... #Workup
Intraoperative Tachycardia - Guidelines for Crises in Anaesthesia
Tachycardia in theatre is often due to inadequate depth
remember to tailor treatment ... obtain 12-lead ECG ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... syndrome): - Hematologic ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
Increased Airway Pressure - Guidelines for Crises in Anaesthesia

Using these steps from start to end should
reservoir bag and APL ... o Aspiration, pulmonary ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
trolley, anaphylaxis treatment ... arrest, start CPR ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup